Glomerular filtration rate (GFR) during and after STEMI: a single-centre, methodological study comparing estimated and measured GFR

Glomerular filtration rate (GFR) during and after STEMI: a single-centre, methodological study comparing estimated and measured GFR

OBJECTIVES To validate the performance of the most commonly used formulas for estimation of glomerular filtration rate (GFR) against measured GFR during the index hospitalisation for ST-elevation myocardial infarction (STEMI). SETTING Single centre, methodological study. PARTICIPANTS 40 patients with percutaneous coronary intervention-treated STEMI were included between November 2011 and Fe...

FIT to measure glomerular filtration rate ( GFR )

Measured GFR as a confirmatory test for estimated GFR.

Clinical assessment of kidney function is central to the practice of medicine. GFR is widely accepted as the best index of kidney function in health and disease, and accurate values are required for optimal decision making. Estimated GFR based on serum creatinine is now widely reported by clinical laboratories, and in most circumstances, estimated GFR is sufficient for clinical decision making....

SERUM CYSTATIN C AS A NEW MARKER OF GLOMERULAR FILTRATION RATE (GFR)

Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...

Assessing kidney function--measured and estimated glomerular filtration rate.

From the Division of Nephrology, Tufts– New England Medical Center, Boston (L.A.S., A.S.L.); the Department of Epidemiology, Johns Hopkins Medical Institutions, Baltimore (J.C.); and the Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland (T.G.). Address reprint requests to Dr. Stevens at Tufts– New England Medical Center, 750 Washington St., Box 391, Boston, MA 0...